Purine nucleosides
Chem-Impex International, Inc. N2-Isobutyryl-2'-deoxyguanosine | 68892-42-2 | MFCD00010060 | 25G
N2-Isobutyryl-2'-deoxyguanosine, 68892-42-2, MFCD00010060, 25G
Medchemexpress LLC 2'-Deoxyadenosine monohydrate | 16373-93-6 | 99.9% | 269.26 | 25 G
2'-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. It also inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation, activates caspase-3, promotes apoptosis, inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH), and inhibits the growth of various cells, demonstrating an anticancer effect on colon cancer.
- Inhibits glucose-stimulated insulin release.
- Inhibits glucose-stimulated increases in islet cyclic AMP accumulation.
- Activates caspase-3 and promotes apoptosis.
- Inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH).
- Inhibits the growth of various cells.
- Has an anticancer effect on colon cancer.
- Appears as a solid, white to off-white substance.
- Initial source is microorganisms (Streptomyces jiujiangensis).
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | 99.21% | 267.24 | 100 MG
2'-Deoxyguanosine (Standard) is an analytical standard of 2'-Deoxyguanosine, intended for research and analytical applications. It is a purine nucleoside with various biological activities, including inducing DNA division in mouse thymus cells and acting as a potent cell division inhibitor in plant cells. It also inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively.
- Analytical standard for 2'-Deoxyguanosine.
- Intended for research and analytical applications.
- Purine nucleoside with various biological activities.
- Induces DNA division in mouse thymus cells.
- Potent cell division inhibitor in plant cells.
- Inhibits clonal growth of HL-60 and K562 leukemia cells (IC50 values of 50 and 80 μM).
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
Medchemexpress LLC 2'-Deoxyguanosine (standard) | 961-07-9 | MFCD00080300 | 99.2% | 267.24 | 50 MG
2'-Deoxyguanosine (Standard) is the analytical standard for 2'-Deoxyguanosine. It is intended for research and analytical applications. This purine nucleoside exhibits diverse biological activities, including inducing DNA division in mouse thymus cells and acting as a potent cell division inhibitor in plant cells. In vitro, it inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively.
- Analytical standard for 2'-deoxyguanosine
- Intended for research and analytical applications
- Induces DNA division in mouse thymus cells
- Potent cell division inhibitor in plant cells
- Inhibits clonal growth of HL-60 and K562 leukemia cells
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Cambridge Isotope Laboratories 2-Deoxyadenosine 5-triphosphate ammonium salt (13C10 98% 15N5 96-98%) CP 90% (in solution) 20 umol
2-Deoxyadenosine 5-triphosphate ammonium salt (13C10 98% 15N5 96-98%) CP 90% (in solution) 20 umol
Medchemexpress LLC Malvidin-3-O-arabinoside chloride | 28500-04-1 | 97.10% | 498.86 | 1 MG
Malvidin-3-O-arabinoside chloride ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy. It upregulates LAMP-1 expression, restores lysosomal acidity, strengthens lysosomal functions, and stimulates phosphorylation of AMP-activated protein kinase (AMPK).
- Upregulates LAMP-1 expression
- Restores lysosomal acidity
- Strengthens lysosomal functions
- Stimulates phosphorylation of AMP-activated protein kinase (AMPK)
- Inhibits excess ROS generation
- Enhances GSH level
- Enhances autophagy flux
- Up-regulates the LC3-II/LC3-I ratio
Medchemexpress LLC 2'-deoxyadenosine | 958-09-8 | MFCD00005754 | 251.24 g/mol | C10H13N5O3 | 500 MG
2'-deoxyadenosine is an adenine nucleoside supplied for research and analytical applications. The compound has been reported to inhibit glucose-stimulated insulin release, activate caspase-3 and promote apoptosis, and inhibit S-adenosyl-L-homocysteine hydrolase (SAHH).
- Adenine nucleoside for research applications.
- Modulates insulin-stimulated cAMP accumulation and insulin release.
- Promotes apoptosis via caspase-3 activation.
- Inhibits S-adenosyl-L-homocysteine hydrolase (SAHH).
- Available from suppliers in small research quantities (supplier pack indicated as 500 MG in provided row data).
Sigma Aldrich Fine Chemicals Biosciences MCOPPB trihydrochloride hydrate >98% (HPLC) | Purity: >98% (HPLC) | 1028969-49-4 (free base) | 25MG
MCOPPB trihydrochloride hydrate >98% (HPLC) | Purity: >98% (HPLC) | 1028969-49-4 (free base) | 25MG
Medchemexpress LLC 2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate | 2483830-27-7 | 99.7% | 284.15 | 1 MG
2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate | 2483830-27-7 | 99.7% | 284.15 | 1 MG
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate-d14 (dilithium) (dATP-d14 (dilithium)) | 2687960-68-3 | 97.10% | 517.13 | 1 MG
2'-Deoxyadenosine-5'-triphosphate-d14 (dATP-d14) dilithium is deuterium labeled 2'-Deoxyadenosine-5'-triphosphate. It is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase. This product is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Deoxyguanosine triphosphate trisodium solution | 93919-41-6 | 99.95% | 573.13 | 28.66 MG
Deoxyguanosine triphosphate (dGTP) trisodium solution (100mM) is a nucleotide precursor in cells for DNA synthesis. It is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification. Deoxyguanosine triphosphate is abnormally elevated in the red blood cells of individuals with immunodeficiency related to purine nucleoside phosphorylase deficiency, and it can be regarded as a potential toxic metabolite.
- Nucleotide precursor for DNA synthesis.
- Used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.